Avivia is an independent pharmaceutical contract R&D organization in the Netherlands that offers a unique complementary range of pharmaceutical services in the field of:
We serve your organization
Generic drug companies, universities, big pharma, excipient manufacturers, hospitals, specialty pharma, small drug development organizations and even investment firms … our customer base is very diverse.
Our pharmaceutical development and technology expertise and capabilities are centered around the development of value-added generics, life cycle management of branded medicines, and complex formulation and chemistry, manufacturing and control (CMC) development of finished dosage forms based on new chemical entities (NCEs).
From life cycle management to new chemical entities
From ad-hoc pharmaceutical development services to full CMC development programs
Expeditious support services and full CMC development programs

Pharmaceutical R&D Services

Analytical R&D Services
Our pharmaceutical analysis experts know what it takes to bring a pharmaceutical product to the market, from discovery, feasibility to cGMP. Having worked with more than 100 unique molecules and even more formulations, we may state that we have faced the most difficult pharmaceutical CMC challenges involved. Avivia offers flexible comprehensive pharmaceutical characterization, stability, forced degradation and compatibility studies, method development and transfer, problem solving and troubleshooting.Predictive and Biorelevant Dissolution Testing Services
Our dissolution platform takes release testing to the highest level. The experience and knowledge-based dissolution testing services focuses primarily on supporting pharmaceutical formulation development and problem solving. Ideally clinical data is used to tune and validate the dissolution method(s). For us dissolution testing is never a routine test. Our dissolution laboratory is equipped with all relevant dissolution techniques (i.e. USP apparatus I, II, III and IV), and more importantly, we know how and when to apply each system in support of pharmaceutical formulation development, troubleshooting and optimization.Excipient Characterization and Deformulation Services

Team work
At Avivia we work in small multidisciplinary pharmaceutical expert teams, allowing the analytical researcher to be directly involved in the process of pharmaceutical formulation development. This rare approach results in an extremely efficient setting. For example: the knowledgeable researcher can develop effective dissolution methods, and significantly more important information can be derived from each dissolution test. Educated observations made by the researcher during and at the end of the dissolution test provide valuable data about disintegration, hydration, swelling, erosion, particle size, granulation and coating properties, floating, cone formation, sticking, etc. Discussing these observations during interactions with the pharmaceutical developer offers additional guidance in the evaluation of dissolution profiles, release mechanisms, excipient performance and setting process parameters.Transfer to cGMP
