Avivia Pharmaceutical Formulation Services

Having decades of hands-on experience with a wide range of (complex) pharmaceutical technologies and many different types of drug products, our pharmaceutical development experts are able to fully execute and/or support the development of any finished dosage form, formula or process, as well as the transfer of a developed product to our new small-scale GMP production area or scale-up to a manufacturing facility.

With our pragmatic and creative development mentality, we deliver what a client needs. We perform best by exploring together the motivations behind their request.

Our pharmaceutical formulation services are supported by strong in-house analytical, dissolution and excipient characterization platforms.

Pharmaceutical Formulation Development

Complex drug product formulations

The execution of many patent workarounds on complex drug products fueled our creative thinking and problem solving. This enables us to attack the most difficult CMC challenges. We love challenges!

Scale up and manufacturing

Our gained scale up and manufacturing expertise/activities yielded a worldwide covering network of CMO’s with whom we are able to accommodate nearly all products and technologies.

Problem solving and troubleshooting

We can do more than execute a solution! We work with the client to craft a more effective one, confirm they’re solving the right problem, or even help them redefine the problem scope completely .

Pharmaceutical Formulations

Avivia offers pharmaceutical formulation development services with small scale GMP batch manufacturing for a variety of drug product dosage forms including:

  • Tablets, capsules and powders
  • Gels and creams
  • Liquids, solutions, suspensions and emulsions
  • Suppositories and pessaries
  • Granules for reconstitution
  • Liquids for sterilization
  • Drug in capsule/vial
Avivia Pharmaceutical Development Services, example product ranges

Examples of recent sponsor projects

  • 3D printing
  • Nano-milling
  • Silica loading
  • Degradable and non-degradable systems
  • Implant technology
  • Microspheres
  • Controlled release coatings
  • Controlled release matrix
  • Taste masking
  • Abuse-proof formulations
  • Solubility enhancement
Avivia Pharmaceutical Development Services, nanospheres
Avivia Pharmaceutical Development Services, nanospheres filled
Avivia Pharmaceutical nanotechnology

Pharmaceutical Formulation Development

Avivia has a pharmaceutical laboratory infrastructure and a flexible small-scale GMP production area with state-of-the-art equipment such as:

• Extrusion
• Spray-drying
• Nano-milling
• Tabletting
• Encapsulation of solids and/or liquids
• Aseptic filling or sterile manufacturing of injectables (vials)
• Blending
• Granulation (high and low shear, fluid bed)
• Vacuum drying and stability cabinets

Avivia pharmaceutical extrusion technology