Pharmaceutical Development Company the Netherlands
Bridging the Gap From API to Pharmaceutical Formulations
Avivia Pharmaceutical Services:
Bridging the Gap From API to Pharmaceutical Formulations
Avivia Pharmaceutical Services:
Avivia provides specialized pharmaceutical development services supporting drug formulation, analytical testing, and manufacturing strategy
Formulation Development
Analytical Services
Dissolution Methods
Excipient Analysis
Formulation Development
From API to Product!
Our comprehensive R&D formulation capabilities combined with our tightly integrated analytical expertise, allow us to support you in advancing your pharmaceutical innovations. Our services leverage a multidisciplinary approach to design formulations, taking into account factors such as bioavailability, stability, and manufacturing scalability.
Our experience spans oral, parenteral and alternative-route drug products, including conventional, poorly soluble, modified-release and complex formulations, supported by tailored problem-solving and troubleshooting strategies.
As we are CMO independent, we select the best manufacturing facility for your product.
From reverse engineering, through in-depth research and development, up to small-scale GMP batch manufacturing, we are dedicated to accelerating your product’s journey to market. Partner with Avivia to streamline your drug development process and achieve faster, more efficient outcomes.
Analytical Services
Dissolving your Challenges!
Avivia provides analytical method development and problem-solving throughout pharmaceutical development. We support challenging method development, stability-indicating methods, product characterization, unknown impurity and degradation investigations, reverse engineering and analytical troubleshooting.
Analytical scientists work closely with our formulation and dissolution teams, allowing analytical results to be interpreted in the context of the drug product and development question. Where required, developed methods can subsequently be transferred to a qualified laboratory for routine or GMP testing.
Dissolution Methods
More than a QC test!
For us, dissolution testing is far from a routine test, it is an essential tool in guiding pharmaceutical formulation development. Small multidisciplinary teams integrate dissolution test observations with pharmaceutical development discussions and clinical data, offering valuable insights into formulation factors and leading to more informed decision-making.
Our highly skilled team is dedicated to developing advanced predictive and biorelevant methods, empowering you to make well-informed R&D choices. These sophisticated methods allow our customers to proceed with clinical testing with confidence. We provide a complete range of dissolution apparatus, from Apparatus I and II to the more advanced Apparatus III and IV.
Excipient Analysis
For what is not on the COA!
Excipients are essential to pharmaceutical formulations, influencing everything from stability to bioavailability. However, since many excipients are derived from natural sources, they often exhibit variability in purity, reactivity, and functionality across different suppliers and even between batches. These inconsistencies can make it challenging to maintain control over product performance and safety.
Excipia is Avivia’s specialized excipient analysis and characterization platform, providing excipient identification and quantification, characterization of Functionality Related Characteristics (FRCs), supplier and batch comparison, deformulation and investigation of excipient variability and chemical reactivity. These capabilities support formulation development, troubleshooting and the investigation of drug product stability and performance.
Formulation Development
From API to Product!
Our comprehensive R&D formulation capabilities combined with our tightly integrated analytical expertise, allow us to support you in advancing your pharmaceutical innovations. Our services leverage a multidisciplinary approach to design formulations, taking into account factors such as bioavailability, stability, and manufacturing scalability.
Our experience spans oral, parenteral and alternative-route drug products, including conventional, poorly soluble, modified-release and complex formulations, supported by tailored problem-solving and troubleshooting strategies.
As we are CMO independent, we select the best manufacturing facility for your product.
From reverse engineering, through in-depth research and development, up to small-scale GMP batch manufacturing, we are dedicated to accelerating your product’s journey to market. Partner with Avivia to streamline your drug development process and achieve faster, more efficient outcomes.
Analytical Services
Dissolving your Challenges!
Avivia provides analytical method development and problem-solving throughout pharmaceutical development. We support challenging method development, stability-indicating methods, product characterization, unknown impurity and degradation investigations, reverse engineering and analytical troubleshooting.
Analytical scientists work closely with our formulation and dissolution teams, allowing analytical results to be interpreted in the context of the drug product and development question. Where required, developed methods can subsequently be transferred to a qualified laboratory for routine or GMP testing.
Dissolution Methods
More than a QC test!
For us, dissolution testing is far from a routine test, it is an essential tool in guiding pharmaceutical formulation development. Small multidisciplinary teams integrate dissolution test observations with pharmaceutical development discussions and clinical data, offering valuable insights into formulation factors and leading to more informed decision-making.
Our highly skilled team is dedicated to developing advanced predictive and biorelevant methods, empowering you to make well-informed R&D choices. These sophisticated methods allow our customers to proceed with clinical testing with confidence. We provide a complete range of dissolution apparatus, from Apparatus I and II to the more advanced Apparatus III and IV.
Excipient Analysis
For whats not on the COA!
Excipients are essential to pharmaceutical formulations, influencing everything from stability to bioavailability. However, since many excipients are derived from natural sources, they often exhibit variability in purity, reactivity, and functionality across different suppliers and even between batches. These inconsistencies can make it challenging to maintain control over product performance and safety.
Excipia is Avivia’s specialized excipient analysis and characterization platform, providing excipient identification and quantification, characterization of Functionality Related Characteristics (FRCs), supplier and batch comparison, deformulation and investigation of excipient variability and chemical reactivity. These capabilities support formulation development, troubleshooting and the investigation of drug product stability and performance.
Drug Development Expertise
Based in Nijmegen, Avivia is a leading pharmaceutical development company in the Netherlands supporting pharma companies across Europe and globally.
Pharmaceutical Company in the Netherlands
Pharmaceutical Development Partner for Pharma Companies
Our diverse customer base spans across Big Pharma, specialty pharma, emerging drug development firms, generic drug companies, universities, excipient manufacturers, law firms, and venture capital firms. While our core expertise lies in wet-lab product development, we also offer hands-on support in areas like IP protection, investor due diligence, upscaling, deformulation analysis, and life cycle management strategy.
By serving a broad range of industries with unique needs, we continuously grow stronger and more versatile in meeting your challenges.
Whether it’s protecting or creating new formulation patents for originator products, or navigating established patents for generic drug development, we continuously pursue innovative IP opportunities to maximize product value. Our team holds over 30 granted patents across a diverse range of drug products.
Patents are in our DNA !
IP creation, protection and evasion
Why Choose Avivia
- CMO-independent development and manufacturing strategy
- Experience with complex and unconventional formulations
- Integrated formulation, analytical and dissolution development
- Specialized excipient characterization through Excipia
- Proven experience across 120+ molecules
Avivia in numbers
“Welcome to Avivia! We hope we’ve sparked your interest. Explore our Services and Lab Capabilities sections to discover how we support pharmaceutical, generics, and drug development companies. If you’d like to learn more, feel free to reach out—we’re here to help accelerate your development programs!”
Lee Ayres, Managing Director Avivia BV
Avivia for all
Our diverse customer base spans across Big Pharma, specialty pharma, emerging drug development firms, generic drug companies, universities, excipient manufacturers, law firms, and venture capital firms. While our core expertise lies in wet-lab product development, we also offer hands-on support in areas like IP protection, investor due diligence, upscaling, deformulation analysis, and life cycle management strategy.
By serving a broad range of industries with unique needs, we continuously grow stronger and more versatile in meeting your challenges.
IP creation, protection and evasion
Whether it’s protecting or creating new formulation patents for originator products, or navigating established patents for generic drug development, we continuously pursue innovative IP opportunities to maximize product value. Our team holds over 30 granted patents across a diverse range of drug products. Patents are in our DNA!
Avivia in numbers
“Welcome to Avivia! We hope we’ve sparked your interest. Explore our Services and Lab Capabilities sections to discover how we support pharmaceutical, generics, and drug development companies. If you’d like to learn more, feel free to reach out—we’re here to help accelerate your development programs!”
Lee Ayres, Managing Director Avivia BV